Valerian

Valerian's mechanism of action is related, among other things, to inhibiting the reuptake of γ-aminobutyric acid and stimulating the release of GABA from nerve endings. Furthermore, isolated valerenic acid prevents the enzymatic degradation of GABA. Increasing GABA concentration causes the opening of ion channels in the nerve cell membrane and increased chloride ion flow into the cell. This results in reduced neuronal excitability and inhibited responses to stimuli.

• Valerian can also be an alternative to traditional anti-anxiety medications, which cause many side effects.
• It also has positive effects when combined with other herbs with calming properties, such as lemon balm leaves and hop cones. Valerian root preparations should not be used for longer than a month, as they may cause side effects such as nausea and abdominal pain. Pregnant and breastfeeding women should not take them.